Fig. 1.

Genes mirror geography around the Mediterranean coast. (A) Geographic distribution of the populations included in this study. (B) Projection on top two principal components of samples from 25 populations genotyped on ∼75,000 genome-wide autosomal SNPs. A clear cline is observed with Anatolia (Cappadocia) connected to Southern Europe through the bridge of the islands of the Dodecanese and Crete. Bedouins and Yemenites drift toward Central-South Asia. No apparent gene flow between Northern Africa and the Southern coast of Europe is observed. (C) Projection on top two principal components of samples from 30 populations genotyped on the same set of SNPs presented in B. Northern European populations have now been added; Bedouins and Yemenites were removed. The cline now continues through Central and Northern Europe.