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. 2014 Jun 10;111(25):9181–9186. doi: 10.1073/pnas.1405411111

Fig. 2.

Fig. 2.

MiR-17-92 and miR-106b-25 deficient mice are susceptible to atrial fibrillation. Simultaneous recordings of simultaneous surface ECG (lead I) and intracardiac electrograms in wild-type (wt) (A), miR-17-92 null/+ (miR-17-92 het) (B), miR-106b-25 null/+ (miR-106b-25 het) (C), and miR-106b-25null/null (miR-106b-25 homo) (D) mice after burst pacing. Absent P-waves and irregular RR intervals suggest pacing-induced AF in miR-17-92 het (B) and miR-106b-25 homo (D) mice. (E) The incidence of inducible AF in different genotypes compared with wt mice are summarized in the bar graph. (F) The duration of the longest inducible AF episode in different genotypes compared with wt mice is summarized in the bar graph. *P < 0.05, **P < 0.01.