Table 5.

Spearman’s Rho correlations and multivariable regression coefficients between biochemical measures and change in BMD after 1 year

Variable	∆QCT BMD Total Hip, mg/cm3		∆QCT Trabecular Spine, mg/cm3		∆QCT Cortical Spine, mg/cm3		∆DXA BMD Total Hip, g/cm2		∆DXA BMD Spine, g/cm2
	Rhoa	Coefficientb	Rhoa	Coefficientb	Rhoa	Coefficientb	Rhoa	Coefficientb	Rhoa	Coefficientb
Baseline
TRAP-5b	−0.27c	−0.28c	−0.01	—	−0.14	—	−0.09	—	−0.11	—
FGF23	0.08	—	−0.16	—	0.01	—	−0.01	—	−0.39d	−0.33e
P1NP	0.25c	0.23	0.12	—	0.31c	0.30c	0.02	—	0.22	—
Sclerostin	−0.37e	−0.31c	−0.01	—	0.08	—	−0.06	—	−0.10	—
Change at 1 yr								—
∆Sclerostin	0.12	—	−0.36e	−0.40e	0.13	—	0.02	—	0.32c	0.28
∆Intact PTH	0.02	—	0.35e	0.36c	−0.03	—	−0.16	—	−0.07	—

Regression coefficients are standardized and adjusted for age group, sex, race, and BMI (n=65–78). Significance for multiple correlations was set at P<0.01 and P<0.05 for multivariable regressions.

^aBivariate correlation Rho.

^bMultivariable regression coefficient.

^cP<0.05.

^dP<0.001.

^eP<0.01.