Table 4.
Sequence variants in the PDGFR-α, EGFR, KRAS and KIT genes
| Gene | Exon | Nucleotide alt. | Amino acid subst. | No. | Interpretation | dbSNP |
|---|---|---|---|---|---|---|
|
PDGFR-α |
10 |
- |
- |
4 |
wild type |
- |
| |
12 |
c.A1701G |
p.P567P |
4 |
SNP |
rs1873778 |
| |
14 |
- |
- |
4 |
wild type |
- |
| |
18 |
- |
- |
4 |
wild type |
- |
|
EGFR |
18 |
- |
- |
4 |
wild type |
- |
| |
19 |
- |
- |
4 |
wild type |
- |
| |
20 |
c.G2361A |
p.Q787Q |
3 |
SNP |
rs1050171 |
| |
20 |
- |
- |
1 |
wild type |
- |
| |
21 |
- |
- |
4 |
wild type |
- |
|
KRAS |
2 |
- |
- |
4 |
wild type |
- |
| |
3 |
- |
- |
4 |
wild type |
- |
|
KIT |
9 |
- |
- |
4 |
wild type |
- |
| |
11 |
- |
- |
4 |
wild type |
- |
| |
13 |
- |
- |
4 |
wild type |
- |
| 17 | - | - | 4 | wild type | - |
No. Number of patients; dbSNPhttp://www.ncbi.nlm.nih.gov/SNP/; SNP single nucleotide polymorphism; Nucleotide alt. Nucleotide alteration; Amino acid subst. Amino acid substitution.