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. Author manuscript; available in PMC: 2014 Jul 2.
Published in final edited form as: J Comp Neurol. 2012 Apr 15;520(6):1198–1211. doi: 10.1002/cne.22768

Figure 3.

Figure 3

Choline acetyltransferase (ChAT)-positive Lis1+/− sympathetic preganglionic (SPNs) and somatic motor neurons (SMNs) do not separate completely during development. A,C,E,G: E13.5 (A), 14.5 (C), 17.5 (E), and P0 (G) Lis1+/+ SPNs are found in the intermediolateral horn (IML). As development proceeds, the distance between the SPNs and SMNs increases (A, dSPN-SMN+/+). B,D,F,H: The separation between SPNs and SMNs is smaller in E13.5 Lis1+/− (B, dSPN-SMN+/-) than in Lis1+/+ mice and also at E14.5 (D), E17.5 (F), and P0 (H). Scale bar = 100 μm in A (applies to A–H).