TABLE 2.
Age | Dorsoventral length of SPNs (dSPN) | Distance between SPNs and SMNs (dSPN-SMN) | Dorsoventral length of PPNs (dPPN) | Distance between PPNs and SMNs (dPPN-SMN) |
---|---|---|---|---|
E13.5 | ||||
+/+ | 0.208 ± 0.005 | 0.081 ± 0.007 | 0.244 ± 0.039 | nd |
+/− | 0.266 ± 0.004** | 0.029 ± 0.004** | 0.295 ± 0.017 | nd |
E14.5 | ||||
+/+ | 0.138 ± 0.003 | 0.211 ± 0.004 | 0.119 ± 0.006 | 0.274 ± 0.022 |
+/− | 0.246 ± 0.006** | 0.080 ± 0.008** | 0.203 ± 0.011** | 0.168 ± 0.030* |
E17.5 | ||||
+/+ | 0.112 ± 0.003 | 0.270 ± 0.006 | 0.137 ± 0.006 | 0.464 ± 0.006 |
+/− | 0.218 ± 0.007** | 0.132 ± 0.006** | 0.221 ± 0.008** | 0.322 ± 0.012** |
P0 | ||||
+/+ | 0.104 ± 0.003 | 0.322 ± 0.008 | 0.152 ± 0.008 | 0.521 ± 0.019 |
+/− | 0.275 ± 0.146** | 0.182 ± 0.011** | 0.304 ± 0.025** | 0.329 ± 0.026** |
Abbreviations: PPN, parasympathetic preganglionic neuron; SMN, somatic motor neuron; SPN, sympathetic preganglionic neuron; nd, not done (unable to measure due to indistinct boundaries between neuronal populations).
All distances were normalized with respect to the total gray matter length along the dorsoventral axis to account for developmental variation in spinal cord sizes.
P < 0.01.
P < 0.0001.