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. 1999 Feb 1;103(3):383–391. doi: 10.1172/JCI4901

Figure 3.

Figure 3

Food and water intake is normal in freely fed CCK-AR–/– mice (a) Twenty-four hour intake of water and Purina rodent laboratory chow are not significantly different (P > 0.05) between wild-type and CCK-AR–/– mice that were fed ad libitum. Average daily intake (mean ± SEM) over a 19-day period is shown. This study included 18 wild-type (WT) and 16 CCK-AR–/– mice. Student's t values for comparison between wild-type and CCK-AR–/– mice were: t(14) = 0.69, P = 0.50 (males, water); t(14) = 0.59, P = 0.57 (males, chow); t(16) = –1.02, P = 0.32 (females, water); and t(16) = 1.95, P = 0.07 (females, chow). (b) Normal diurnal variation in food intake of CCK-AR–/– mice. Eight wild-type and seven CCK-AR–/– mice were allowed ad libitum access to Purina rodent laboratory chow. Average intake of chow (mean ± SEM) during the light and dark cycles, each 12 h long, was recorded over a 14-day period. There was no significant difference (P > 0.05) between the intake of wild-type (WT) and CCK-AR–/– mice during either the light or the dark period. Student t values for comparison between wild-type and CCK-AR–/– mice were: t(13) = –0.74, P = 0.48 (food intake, dark); t(13) = 1.57, P = 0.14 (food intake, light).