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. 1999 Feb 1;103(3):347–354. doi: 10.1172/JCI4953

Figure 1.

Figure 1

Neuronal vulnerability to combined glucose and oxygen deprivation is increased in hippocampal neurons lacking gelsolin (gsn). Cultures from gsn+/+, gsn+/–, and gsn–/– mice were subjected to combined G/O deprivation or medium change without G/O deprivation (control) for 30 min. Cultures were then incubated for an additional 20 h in Locke's solution and neuronal survival was quantified. Values are the mean and SE of determinations made in four separate cultures. *P < 0.05 compared with the value in gsn+/+ cultures exposed to G/O deprivation. **P < 0.01 compared with value in gsn+/+ cultures exposed to G/O deprivation, and P < 0.05 compared with the value in gsn+/– cultures exposed to G/O deprivation. ANOVA followed by Scheffe's post hoc tests. G/O, glucose/oxygen.