Figure 2.

In vivo expression of ECD mutant alleles. PBMC were isolated from patients P4, P6, P10, and P11, and CD95 expression was quantified by flow cytometry using the anti-CD95 MAB, UB2. PBMC staining with an isotype control antibody is indicated by shaded histograms. The percent of CD95 cells for each individual is shown. The corresponding mean channel fluorescence results were as follows: P4 (18.2), P6 (17.1), P10 (34.2), and P11 (16.8). PBMC, peripheral blood mononuclear cells; MAB, monoclonal antibody.