Table 2.

Effect of patient characteristics on observed sensitivity and specificity of the immunochromatographic RSV test. NCH-SOB, National Children’s Hospital severity of bronchiolitis scale. All vital signs refer to the first set obtained at triage.

	Sensitivity (95% CI)	Specificity (95% CI)
Age
< 2 months	78.3 (71.4, 84.2)	69.5 (63.6, 75.0)
≥ 2 months	81.7 (71.6, 89.4)	59.5 (48.3, 70.1)
Respiratory rate
> 60	79.7 (73.8, 84.8)	69.7 (64.3, 74.8)
≤ 60	77.1 (59.9, 89.6)	44.4 (27.9, 61.9)
Pulse oximetry
Sa O2 >92%	79.5 (73.8, 84.4)	67.7 (62.5, 72.7)
Sa O2≤92%	77.8 (52.4, 93.6)	53.3 (26.6, 78.7)
Work of breathing
Normal/Mild	76.9 (68.2, 84.2)	62.9 (53.8, 71.4)
Moderate/severe	81.8 (74.3, 87.8)	69.8 (63.3, 75.8)
Heart Rate
<98th centile	79.7 (73.5, 85.0)	66.9 (60.9, 72.5)
≥98th centile	78.2 (65.0, 88.2)	67.9 (56.6, 77.8)
Rectal temperature
<38°C	77.8 (62.9, 88.8)	67.9 (56.8, 77.6)
≥38°C	79.7 (73.7, 84.9)	66.9 (60.9, 72.5)
NCH-SoB
Mild	69.4 (51.9, 83.7)	55.8 (41.3, 69.5)
Moderate	81.8 (75.3, 87.3)	70.1 (63.8, 76.0)
Severe	71.4 (47.8, 88.7)	62.1 (42.3, 79.3)