X-axis shows interictal periorbital withdrawal scores in response to monofilament (4g) stimulation of the periorbital region during the interictal period on Day 8. Y-axis shows distance traveled on Day 7. Female 10µl PBS group, n = 5; female 10µl IS group, n = 6; female 20µl PBS group, n = 3, female 20µl IS group, n = 5. The data are shown with a general linear regression with a goodness of fit analysis performed using ANOVA F-test. The correlation is statistically significant (P = .0003).