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Mitochondrial GSH redox cycle and interaction with other antioxidant defenses. Detoxification of harmful lipid peroxides (Lipid-OOH) to their corresponding hydroxides (lipid-OH) by glutathione peroxidase 4 (GPX4) and glutathione-S-transferases (GST). Control of mitochondrial protein glutathionylation (Prot-S-SG, Prot -SH) by glutaredoxin (GRX2) and thioredoxin 2 (TRX2).
