. Author manuscript; available in PMC: 2014 Jul 2.

Published in final edited form as: J Alzheimers Dis. 2013;36(2):275–284. doi: 10.3233/JAD-122050

Table 4.

Odds ratios (ORs) and 95% confidence intervals (CIs) of subjective cognitive impairment (SCI) and cognitive impairment no dementia (CIND) in relation to chronic diseases: results from co-twin matched case-control analysis for SCI- or CIND-discordant twin pairs (N=1,720 and N=926) using Conditional Logistic Regression.

	SCI		CIND

	Model 1^a OR (95% CI)	Model 2^b OR (95% CI)	Model 1^a OR (95% CI)	Model 2^b OR (95% CI)
Mental	1.5 (1.0–2.2)	1.1 (0.7–1.7)	1.5 (0.9–2.5)	1.2 (0.7–2.2)
Circulatory	1.3 (1.1–1.7)^*	1.7 (0.9–1.5)	1.2 (0.9–1.6)	1.2 (0.9–1.7)
Musculoskeletal	1.5 (1.2–1.8)^**	1.4 (1.1–1.7)^**	1.2 (0.9–1.6)	1.0 (0.7–1.3)
Respiratory	1.5 (1.1–2.1)^*	1.5 (1.1–2.1)^*	1.1 (0.7–1.6)	1.0 (0.7–1.6)
Endocrine	1.3 (0.9–1.7)	1.2 (0.9–1.6)	1.4 (1.0–2.0)	1.3 (0.9–1.9)
Gastrointestinal	1.8 (1.4–2.3)^**	1.6 (1.2–2.2)^**	1.0 (0.7–1.5)	1.0 (0.7–1.5)
Urological	1.4 (1.1–1.7)^**	1.4 (1.1–1.7)^**	1.0 (0.7–1.3)	0.9 (0.7–1.5)
Malignancy	0.9 (0.7–1.3)	0.9 (0.6–1.2)	1.7 (1.1–2.7)^*	1.7 (1.0–2.8)^*

Conditional Logistic Regression model adjusted for education and zygosity;

Conditional Logistic Regression model adjusted for education, zygosity, all chronic diseases, current depressive symptoms and current anxiety;

p<0.05;

^**

p<0.01.