Table 1.

Numbers of Patients Contributing to Subgroup Analyses

			FEV1 Range (% predicted)
	All	Age < 6 yrs	≥ 100	70 to <100	40 to <70	<40
All patients	39,326	9,653	5,573	12,752	7,991	3,357
Age Group
6-12 yrs	13,398	-	4,038	6,926	2,117	317
13-17 yrs	7,698	-	1,293	3,686	2,171	548
18-24 yrs	4,280	-	180	1,364	1,823	913
≥ 25 yrs	4,297	-	62	776	1,880	1,579
Sex, Male	19,930	4,827	2,998	6,497	3,761	1,847
WFA Percentilea
<25th	18,228	3,911	1,791	5,469	4,643	2,414
≥25th	20,988	5,711	3,772	7,255	3,320	930
Signs and Symptomsa
Daily Cough	18,016	2,460	1,683	5,605	5,457	2,811
Daily Sputum	11,087	640	678	3,094	4,156	2,519
Clubbing	20,190	2,139	2,356	6,935	5,880	2,880
Crackles	6,739	392	221	1,338	2,619	2,169
Wheeze	1,778	288	148	483	500	359
Pulmonary Exacerbation Historyb
None	24,777	7,149	4,566	8,793	3,395	874
One	8,438	1,700	757	2,703	2,335	943
Two	3,384	504	167	816	1,163	734
Three or more	2,727	300	83	440	1,098	806
P. aeruginosa Culture Historyc
All Negative	15,572	5,761	2,846	4,885	1,647	433
Any Positive	20,269	2,732	2,295	6,749	5,765	2,728
Indeterminated	4,818	685	607	1,797	1,216	513
Intermittente	4,155	1311	626	1,303	684	231
Chronicf	11,296	736	1,062	3,649	3,865	1,984

^aAs recorded at the index visit

^bNumber of pulmonary exacerbations treated with IV antibiotics in the 12 months prior to the index visit

^cRecorded in the 12 months prior to the index visit

^dOnly one culture result reported

^e≤50% of cultures positive

^f>50% of cultures positive