. Author manuscript; available in PMC: 2014 Jul 2.

Published in final edited form as: J Cyst Fibros. 2011 Jul 30;10(6):453–459. doi: 10.1016/j.jcf.2011.07.003

Table 2.

Median Time (Days) to Treatment during the Follow Up Period with “Any” Antibiotics for a Pulmonary Exacerbation by Patient Subgroup.

			FEV₁ Range (% predicted)
	All	\|Age <6 yrs\|	≥ 100	70 to <100	40 to <70	<40
All patients	294	(>365)^a	(>365)	299	147	112

Age Group
6-12 yrs	364	-	(>365)	365	179	98
13-17 yrs	202	-	(>365)	258	133	96
18-24 yrs	143	-	312	203	127	98
≥ 25 yrs	155	-	302	252	161	125

Sex
Male	329	(>365)	(>365)	343	168	120
Female	266	(>365)	(>365)	268	133	98

WFA Percentile^b
<25^th	238	(>365)	(>365)	299	133	106
≥25^th	357	(>365)	(>365)	299	168	121

Signs and Symptoms^b
Daily Cough	189	(>365)	364	224	133	107
Daily Sputum	154	317	280	210	128	108
Clubbing	203	(>365)	(>365)	266	135	110
Crackles	133	273	(>365)	203	121	103
Wheeze	218	(>365)	(>365)	308	136	126

Pulmonary Exacerbation History^c
None	398	(>365)	(>365)	(>365)	231	189
One	193	(>365)	280	193	147	124
Two	119	259	168	121	98	102
Three or more	77	168	134	84	69	65

P. aeruginosa Culture History^d
All Negative	(>365)	(>365)	(>365)	(>365)	197	139
Any Positive	187	(>365)	316	216	131	105
Indeterminate^e	222	(>365)	308	252	175	133
Intermittent^f	282	(>365)	(>365)	271	159	91
Chronic^g	147	268	276	189	119	98

When time >365 days, less than half of subjects were treated with “any” antibiotics during the follow up period

As recorded at the index visit

Number of pulmonary exacerbations treated with IV antibiotics in the 12 months prior to the index visit

Recorded in the 12 months prior to the index visit

Only one culture result reported

≤50% of cultures positive

>50% of cultures positive