Table 3.

Percentage of Patients Treated with Either “Any” Antibiotics or IV Antibiotics during the Follow Up Period by Patient Subgroup

							FEV1 Range (% predicted)
	All Patients		Age < 6 yrs		≥ 100		70 to <100		40 to <70		<40
	“Any”	IV	“Any”	IV	“Any”	IV	“Any”	IV	“Any”	IV	“Any”	IV
All Patients	55.0	34.1	35.3	18.8	39.5	16.0	55.0	29.2	76.8	57.0	85.7	72.7
Age Group
6-12 yrs	49.8	27.6	-	-	36.5	14.5	49.2	25.2	71.8	54.1	84.5	72.5
13-17 yrs	65.5	41.0	-	-	46.1	19.9	60.7	32.0	79.4	59.0	89.0	79.8
18-24 yrs	76.0	56.1	-	-	54.7	21.9	65.6	39.5	80.6	61.7	86.4	76.5
≥ 25 yrs	75.8	54.6	-	-	51.6	12.9	60.5	33.6	75.7	53.1	84.3	68.2
Sex
Male	52.3	31.2	33.3	17.9	37.9	14.4	51.7	25.2	73.6	53.2	84.1	69.2
Female	57.8	37.1	37.3	19.8	41.4	17.7	58.4	33.3	79.6	60.3	87.6	77.0
WFA Percentilea
<25th	60.5	40.9	39.0	23.3	40.6	17.1	55.2	30.1	78.9	59.9	86.8	74.9
≥25th	50.2	28.2	32.7	15.8	39.0	15.4	54.7	28.4	74.0	53.1	82.6	67.1
Signs and Symptomsa
Daily Cough	67.9	46.7	44.8	26.2	49.5	21.5	62.6	36.3	79.8	60.4	86.8	74.2
Daily Sputum	74.8	54.8	52.9	33.3	57.5	25.7	65.9	40.0	80.3	61.9	87.0	74.6
Clubbing	65.5	43.5	43.8	24.0	42.7	16.7	59.5	32.2	79.3	59.7	86.4	74.0
Crackles	78.1	60.9	58.0	41.6	46.0	25.6	67.0	42.7	82.3	64.8	86.7	74.5
Wheeze	61.5	43.2	40.0	27.3	40.2	18.5	53.6	31.7	75.2	54.3	79.3	66.3
Pulmonary Exacerbation Historyb
None	42.4	19.4	28.9	12.7	34.4	11.1	46.2	19.3	64.0	37.8	72.1	49.3
One	68.9	47.4	48.6	30.3	58.0	32.6	69.3	43.1	80.2	60.1	85.5	71.0
Two	82.8	67.9	61.1	45.3	73.2	48.7	82.1	61.3	89.4	76.4	90.2	81.9
Three or more	92.0	84.4	68.9	55.5	81.4	69.4	93.0	81.9	95.6	89.0	96.2	91.8
P. aeruginosa Culture Historyc
All Negative	38.4	22.5	29.5	16.1	29.2	12.8	41.4	22.3	66.4	50.2	77.9	66.0
Any Positive	69.1	44.6	48.4	25.1	53.0	20.2	65.3	35.0	80.8	60.5	87.8	75.1
Indeterminated	63.9	36.3	45.2	22.9	53.5	20.2	61.7	31.3	74.8	50.0	82.8	64
Intermittente	56.5	32.8	44.6	21.7	44.7	17.9	58.2	38.9	76.3	55.7	86.9	77.3
Chronicf	75.9	52.5	58.3	33.3	57.6	21.6	69.6	50.0	83.5	64.6	89.1	77.7

^aAs recorded at the index visit

^bNumber of pulmonary exacerbations treated with IV antibiotics in the 12 months prior to the index visit

^cRecorded in the 12 months prior to the index visit

^dOnly one culture result reported

^e≤50% of cultures positive

^f>50% of cultures positive