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Scoring of p16INK4a overexpression and its association with HPV DNA in HNSCC and OPSCC.
| Scoring | p16INK4a expression
|
Total | |||||
|---|---|---|---|---|---|---|---|
| p16INK4a no or lower expression (<3)
|
p16INK4a overexpression (≥3)
|
||||||
| 0 | 1 | 2 | 3 | 4 | |||
| HNSCC | HPV DNA+ | 18 | 3 | 1 | 1 | 24 | 47 |
| HPV DNA− | 92 | 3 | 3 | 1 | 4 | 103 | |
| OPSCC | HPV DNA+ | 4 | 1 | 0 | 1 | 19 | 25 |
| HPV DNA− | 27 | 0 | 1 | 0 | 0 | 28 | |
HPV, human papillomavirus; HNSCC, head and neck squamous cell carcinoma; OPSCC, oropharyngeal squamous cell carcinoma.
