Table 1.
Sample characteristics, adipokines and hormones related to body composition in HIV-uninfected controls and HIV-infected patients
| HIV-uninfected controls | HIV-infected patients | p | |
|---|---|---|---|
| n |
74 |
217 |
|
| Age [years, mean (sd)] |
47.2 (9.7) |
46.6 (11.6) |
0.73 |
| Gender [n (%)] |
|
|
|
| Male |
40 (54.1) |
144 (66.9) |
|
| Female |
34 (45.9) |
73 (33.6) |
0.08 |
| Weight [Kg, mean (sd)] |
71.5 (13.4) |
67.8 (12.3) |
0.03 |
| BMI [(kg/m2), mean (sd)] |
26.3 (4.3) |
35.1 (4.5) |
0.05 |
| Waist circumference [cm, mean (sd)] |
90.7 (11.6) |
91.2 (11.6) |
0.75 |
| Hip circumference [cm, mean (sd)] |
99.8. (7.1) |
94.5 (8.4) |
<0.001 |
| Waist/hip ratio [mean (sd)] |
0.91 (0.08) |
0.96 (0.08) |
<0.001 |
| Arm circumference [cm, mean (sd)] |
30.6 (3.5) |
27.0 (3.0) |
<0.001 |
| Systolic blood pressure [mmHg, mean (sd)] |
122.2 (17.3) |
121.9 (17.5) |
0.99 |
| Diastolic blood pressure [mmHg, mean (sd)] |
78.9 (10.1) |
76.7 (11.3) |
0.24 |
| Glucose [mg/dL, mean (sd)] |
91.7 (12.2) |
107.7 (41.5) |
0.03 |
| Insulin [μU/mL, mean (sd)] |
5.5 (4.9) |
11.2 (10.6) |
<0.001 |
| HOMA [mean (sd)] |
1.3 (1.4) |
3.1 (3.2) |
<0.001 |
| QUICKI [mean (sd)] |
0.39 (0.05) |
0.36 (0.08) |
<0.001 |
| Total cholesterol [mg/dL, mean (sd)] |
217.2 (43.6) |
224.2 (58.0) |
0.26 |
| LDL cholesterol [mg/dL, mean (sd)] |
134.9 (38.8) |
128.5 (49.9) |
0.42 |
| HDL cholesterol [mg/dL, mean (sd)] |
57.4 (14.9) |
46.1 (13.6) |
<0.001 |
| Triglycerides [mg/dL, mean (sd)] |
119.8 (57.6) |
267.5 (182.8) |
<0.001 |
| Uric acid [mg/dL, mean (sd)] |
49.6 (15.4) |
46.8 (15.0) |
0.165 |
| hs-CRP [mg/dL, mean (sd)] |
0.36 (0.54) |
0.45 (0.73) |
0.55 |
| Resistin [ng/mL, mean (sd)] |
15.5 (11.0-22.2) |
10.4 (8.0-13.9) |
<0.001 |
| Adiponectin [μg/mL, mean (sd)] |
5.18 (2.80-7.74) |
2.68 (1.19-5.46) |
<0.001 |
| TNF-α [pg/mL, mean (sd)] |
45.3 (29.9-60.5) |
44.6 (30.1-73.6) |
0.63 |
| Ghrelin [pg/mL, mean (sd)] |
18.6 (10.5-25.4) |
75.0 (47.7-139.5) |
<0.001 |
| Leptin [ng/mL, mean (sd)] |
11.8 (6.3-21.3) |
3.4 (1.9-7.6) |
<0.001 |
| Adiponectin/leptin ratio [mean (sd)] | 1.00 (1.95) | 2.29 (5.87) | 0.02 |