| Addad et al, 2010 [57]
|
Stable coronary artery disease (n = 188) |
Composite endpoint of major adverse cardiovascular events at 1 year was more frequent in subjects homozygous for PlA1 allele |
| Castro et al, 2004 [53]
|
Homozygous for sickle cell anaemia (n = 97) |
No significant association between carriage of the PlA2 allele and risk of occlusive vascular events |
| Galasso et al, 2010 [49]
|
Hypertensive patients with prior cerebrovascular event (74 cases, 100 controls) |
Carriage of the PlA2 allele associated with an increased risk stroke, both in terms of healthy controls and compared to risk of a transient ischaemic attack |
| Komarov et al, 2009 [54]
|
Stable coronary artery disease (n = 287) |
Risk of composite cardiovascular end point was not elevated in patients carrying the PlA2 allele |
| Lalouschek et al, 2007 [64]
|
Cerebrovascular event in patients <60 years old (450 cases, 817 controls) |
No significant association between carriage of the PlA2 allele and risk of stroke or transient ischaemic attack |
| Mustaffa et al, 2009 [50]
|
Malay ischaemic stroke patients (91 cases, 104 controls) |
No difference in allele frequency between stroke patients and healthy blood donors |
| Pongracz et al, 2001 [52]
|
Hungarian stroke patients (234 cases, 173 controls) |
Non-significant increase in carriage of the PlA2 allele among stroke patients >50 years old |
| Streifler et al, 2001 [51]
|
Carotid artery stenosis (n = 153) |
Carriage of the PlA2 allele increased risk of stroke or transient ischaemic attack |
| Yeh et al, 2004 [55]
|
Stroke patients <50 years old (n = 231) |
Carriage of the PlA2 allele was not associated with an increased risk of the composite cardiovascular end point at 1 year |
| Wei et al, 2009 [56]
|
Ischaemic stroke patients (265 cases, 280 controls) |
Distribution of PlA2 allele was not different between ischaemic stroke group or control group |
