Clinical pharmacy support |
Benefit within 3 studies with moderate magnitude of effect; SOE moderate |
Benefit in 1 study with moderate magnitude of effect; SOE moderate |
Unable to make a conclusion based on 1 study with imprecise results; SOE insufficient |
No studies; SOE insufficient |
Decision support |
Benefit with large magnitude of effect; SOE moderate |
Studies consistently favor intervention with large magnitude of effect; SOE moderate |
Benefit with moderate magnitude of effect (larger in pre-post studies); SOE moderate |
Unable to conclude due to inconsistent results; SOE insufficient |
Education only |
No benefit; SOE low |
Small to moderate increases in a minority of studies; SOE low |
No benefit; inconsistent results (reductions and increases); low SOE |
No conclusion due to inconsistent and imprecise estimates of effect in 5 studies; SOE insufficient |
Feedback and audit |
Benefit with moderate magnitude of effect; SOE moderate |
Benefit with low magnitude of effect; SOE low |
No conclusion could be made due to conflicting results in few studies; SOE insufficient |
No conclusion due to inconsistent results in 1 included study; SOE insufficient |
Information only |
Unable to make conclusion; SOE insufficient |
No studies; SOE insufficient |
Unable to make conclusion; no difference seen, but study quality was low; SOE insufficient |
No studies; SOE insufficient |
Multicomponent interventions |
Benefit with moderate magnitude of effect; SOE low |
Benefit, with moderate magnitude of effect (larger in observational studies); SOE low |
Unable to make conclusion; although the 1 study reported a large reduction, the study quality was low; insufficient SOE |
No conclusion; 1 study reported a large reduction, but study quality was low; SOE insufficient |
Organizational change |
Benefit with small magnitude of effect; SOE low |
Two studies show benefit with moderate magnitude of effect; SOE low |
No benefit with range of magnitudes of effect; SOE low |
No benefit (for missed school days); SOE low |
Quality improvement and pay-for-performance |
No studies; SOE insufficient |
Observational studies showed benefit, but the RCT did not; benefit with moderate magnitude of effect; SOE low |
No benefit; SOE low |
Unable to draw conclusions; 1 study (with high risk of bias) reported a nonsignificant reduction in schooldays missed; SOE insufficient |