Table 3.

Glucose Uptake and Oxidation

	RER	Rd, mg/kg · min	MCR, ml/kg · min	CHO Ox, mg/kg · min	NOGD, mg/kg · min
Isotope equilibrium
NGT	—	1.50 ± 0.14	1.63 ± 0.14	—	—
IFG	—	1.74 ± 0.17	1.69 ± 0.16	—	—
Euglycemia
NGT	0.85 ± 0.01	1.61 ± 0.07	1.93 ± 0.10	1.17 ± 0.17	0.44 ± 0.16
IFG	0.83 ± 0.02	1.83 ± 0.13	2.23 ± 0.18	0.84 ± 0.23	0.98 ± 0.28
Hyperglycemia
NGT	0.88 ± 0.01	3.21 ± 0.29a	1.87 ± 0.18	1.46 ± 0.19	1.75 ± 0.36a
IFG	0.86 ± 0.01	3.56 ± 0.41a	2.13 ± 0.25	1.22 ± 0.20	2.34 ± 0.45a
Hyperglycemia+fructose
NGT	0.91 ± 0.01b	3.93 ± 0.39	2.22 ± 0.21	1.71 ± 0.18b	2.21 ± 0.43
IFG	0.89 ± 0.01b	3.44 ± 0.40	1.92 ± 0.21	1.56 ± 0.19b	1.88 ± 0.45

Abbreviations: CHO Ox, carbohydrate oxidation rate; RER, respiratory exchange ratio. Values are mean ± SEM calculated from the [6,6-²H₂]glucose tracer. Dashes indicate unknown values.

^aP < .05 compared with prior stage.

^bP < .05 compared with euglycemia.