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. 2014 Jul 2;9(7):e101172. doi: 10.1371/journal.pone.0101172

Figure 5. Agonistic effect of AMD3100 on CXCL12-overexpressing Rin-5F cells.

Figure 5

(A) Viability assay of control and hydrogen peroxide-treated #1 cells grown in the absence or in the presence of AMD3100. The results are expressed as means ± S.E.M. Means not sharing a common letter are significantly different between groups (p<0.05). (B) The effects of AMD3100 treatment on the protein levels of Akt and ERK1/2 kinases and phosphorylated Akt (pAkt) and ERK1/2 kinases (pERK) (left panel), and on the poly(ADP-ribosyl)ation level and PARP-1 presence (right panel) determined by immunoblot analysis in control and hydrogen peroxide-treated #1 cells grown in the absence or in the presence of AMD3100.