Table 5. Pharmacokinetic Parameters of Agelastatin A (1a) Based on a Single 2.5 mg/kg Dose, Intravenous (IV) or Intraperitoneal (IP).

	administration route
PK parameter	intravenous (IV)	intraperitoneal (IP)
AUCa	1742	2946
Cmaxb	4.50 μM	1.65 μM
Tmaxc	2 min	30 min
t1/2d	4 min	1 h

^aAUC = area under the curve.

^bC_max = maximum compound concentration.

^cT_max = time at which C_max occurs.

^dt_1/2 = compound half-life. PK parameters were calculated in GraphPad Prism software.