Table 6. Pharmacokinetic Parameters of 1a and 1j^a.

	2.5 mg/kg dose		5.0 mg/kg dose
PK parameterb	1a	1j	1a	1j
AUC	6260	12 925	4294	6508
Cmax	1.28 μM	4.18 μM	2.30 μm	3.25 μM
Tmax	30 min	15 min	30 min	30 min
t1/2	1.4 h	1.2 h	1 h	45 min

^aParameters calculated from LCMS analysis of time-course monitoring of blood samples after single 2.5 or 5.0 mg/kg IP dose.

^bSee caption in Table 4 for the key.