Table I.

Clinicopathological characteristics and PPM1D expression in patients with colorectal cancer.

		PPM1D expression
Characteristic	n	Low	High	P-value
Total	368	116	252
Age (years)				0.371
<60	144	52	92
≥60	224	64	160
Gender				0.49
Male	208	72	136
Female	160	44	116
Tumor location				0.875
Right colon	80	24	56
Left colon	92	32	60
Rectum	196	60	136
Histology (differentiation)				0.098
Well	172	48	124
Moderate	136	56	80
Poor	60	12	48
Node metastasis				0.0024
N0	160	72	88
N1–3	208	44	164
Distant metastasis				<0.001
No	288	112	176
Yes	80	4	76
TNM stage				0.0016
I	28	12	16
II	112	24	88
III	148	72	76
IV	80	8	72

PPM1D, protein phosphatase, Mg²⁺/Mn²⁺ dependent, 1D.