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. 2014 Jun 2;8(2):527–532. doi: 10.3892/etm.2014.1752

Figure 3.

Figure 3

Overexpression of miR-155 ameliorated the anticancer drug-induced cell proliferation decrease in vitro. (A) Expression of miR-155 was compared following transfection with miR-control or miR-155 mimics (25 nM) in Saos-2 or MG-63 cells. (B) Cell proliferation of Saos-2 or MG-63 cells following miR-155 mimics or miR-control transfection at 25 nM or 50 nM, as determined by a CCK-8 assay. Growth curves showing the cell proliferation following 0.2 μg/ml Dox treatment and miR-155 mimics or miR-control transfecion in (C) Saos-2 and (D) MG-63 cells, as determined by a CCK-8 assay. Independent experiments were performed in triplicate. *P<0.05, **P<0.01 and ***P<0.001, vs. control miR-155, microRNA-155; CCK-8, Cell Counting Kit-8; Dox doxorubicin.