Figure 3. Kinetics of activated or proliferating T-cells in rechallenged, vaccinated and control chimpanzees following challenge.
Frequency of total CD8+T-cells expressing activation or proliferation markers in rechallenged, vaccinated or control animals. A) % CD38+/HLA-DR+ CD8+ T-cells from rechallenged animals B) % Ki67+/Bcl-2-low CD8+ T-cells from rechallenged animals C) % CD38+/HLA-DR+ CD8+ T-cells from vaccinated animals D) % Ki67+/Bcl-2-low CD8+ T-cells from vaccinated animals. E) % CD38+/HLA-DR+ CD8+ T-cells from control animals F) % Ki67+/Bcl-2-low CD8+ T-cells from control animals. PBMCs were gated on CD3+/CD8+ cells.