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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Hepatology. 2014 Jan 28;59(3):803–813. doi: 10.1002/hep.26747

Figure 7. Kinetics of activated or proliferating T-cells in vaccinated and control chimpanzees during immunization and prior to challenge with HCV.

Figure 7

A) % CD38+/HLA-DR+ CD8+ T-cells from vaccinated animals B) % Ki67+/Bcl-2-low CD8+ T-cells from vaccinated animals. C) % CD38+/HLA-DR+ CD8+ T-cells from control animals D) % Ki67+/Bcl-2-low CD8+ T-cells from control animals. E) Frequencies of proliferating CD8+ T-cells expressing HLA-DR either alone or co-expressed with the marker CD38 for vaccinated animals post vaccination and pre-challenge. F) Frequencies of proliferating CD8+ T-cells expressing HLA-DR either alone or co-expressed with the marker CD38 for control animals post mock vaccination and pre challenge. PBMCs were gated on CD3+/CD8+ cells or CD3+/CD4+ cells.