Figure 1. H & E stains illustrating the effects of insulin-containing dermal patches on the morphology of the skin in STZ-induced diabetic rats.

Picture A represents intact secretory ducts (white arrow), stratum basale (yellow arrow) and intact sebaceous glands (red arrow) of the untreated control animals. (Mag 8×500 µm). Picture B represents intact secretory ducts (white arrow), uninjured stratum basale (yellow arrow) and intact sebaceous glands (red arrow) of the PI treated animals. (Mag 8×500 µm). Pictures C represents intact secretory ducts (white arrow), uninjured stratum basale (yellow arrow) and intact sebaceous glands (red arrow) of the subcutaneously insulin treated animals (Mag 12×500 µm).