Table 3. Long tandem duplications with at least 96% identity that occur within a gene locus.
Gene | Length | Copies | Gap | Coding |
NBPF20 | 76181 | 2 | 55 | Y |
NBPF8 | 65137 | 2 | 0 | Y |
CR1 | 54708 | 3 | 0 | Y |
ANKRD30A | 47663 | 2 | 2 | Y |
RBMY1A1 | 47081 | 3 | 0 | Y |
NBPF12 | 44119 | 2 | 31 | Y |
PGA4 | 37662 | 2 | 0 | Y |
TRPM3 | 35986 | 2 | 0 | N |
FCGBP | 31945 | 2 | 0 | Y |
NEB | 31782 | 3 | 0 | N |
NKG2-E | 30864 | 2 | 0 | Y |
TBC1D3C/TBC1D3H | 27063 | 2 | 0 | N |
HCAR1 | 26136 | 2 | 14 | Y |
TTC34 | 22675 | 2 | 22 | N |
DAZ1 | 21690 | 2 | 0 | Y |
NBPF1 | 12620 | 2 | 17 | Y |
NBPF12 | 12568 | 2 | 4 | Y |
BRF1 | 11321 | 2 | 0 | N |
C2orf78 | 10103 | 2 | 58 | Y |
CLEC17A | 8924 | 2 | 0 | Y |
TTN | 8521 | 2 | 0 | Y |
SNTG2 | 8383 | 2 | 1 | N |
IFI16 | 8282 | 2 | 0 | Y |
MUC5B | 7627 | 2 | 1 | Y |
SPDYE3 | 7020 | 5 | 0 | Y |
ERC1 | 5850 | 2 | 23 | N |
HRNR | 5637 | 2 | 0 | Y |
ACRC | 4289 | 2 | 66 | Y |
SPRN | 4144 | 2 | 0 | N |
TMEM132D | 3907 | 2 | 12 | N |
HP/HPR | 3431 | 2 | 4 | Y |
Duplications were identified as described in the Methods. The length indicates the total length of the high-identity tandem duplicons. The gap is the separation between the two highest-identity (long) duplicons, which was required to be less than 100 bp. The duplication is “coding” if a duplicon overlaps at least one exon.
FCGBP has a third duplicon, but with less than 96% identity.
These genes have duplicons that are themselves STRs of lower fidelity; only the copy number for the high-identity long tandem duplication is reported in this table.
The segmental duplication containing NKG2-E overlaps the three genes KLRC1, KLRC2 and KLRC3.