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. 2014 Jul 2;9(7):e101093. doi: 10.1371/journal.pone.0101093

Table 11. Immunological features of autism and schizophrenia.

Feature Autism Schizophrenia
HLA Association Yes [441], [442] Yes [442], [443]
Co-morbidity with autoimmune disease Yes [441], [444][446] Yes [447][449]
Viral triggers for disease Yes [450] Yes [450], [451]
Association with maternal infection during pregnancy. Yes [441] Yes [452]
Autoantibodies Brain-specific antibodies in mothers and probands [441], [446], [453], [454]; Anti-nuclear antibodies [446], [455] Yes [456]
Other Gene expression changes reminiscent of autoimmunity [457]; NK cell dysregulation [458]; Amelioration of aberrant behaviors during fever [459] Various immunological abnormalities [460][462]; differentially expressed genes involve immune pathways [463]