Table 2. Effect of triptolide and SFN on ALT, AST, ALP and LDH in BALB/C mice.
Parameters | Groups | |||
Con | SFN | TP | SFN+TP | |
AST (U/L) | 154.7±32.3 | 170.2±36.9 | 1404.3±457.0b | 171.2±41.2c |
ALT (U/L) | 45.7±6.3 | 65.9±22.5 | 447.2±105.9b | 97.2±29.1a , c |
ALP (U/L) | 263.2±24.9 | 232.6±33.8 | 184.5±29.2 | 183.2±30.1 |
LDH (U/L) | 1455.3±103.0 | 1699.0±365.2 | 4395.7±286.5b | 1221.3±130.6c |
Mice were given vehicle control, SFN (25 mg/kg), TP (1.0 mg/kg), SFN (25 mg/kg)+TP (1.0 mg/kg) by intraperitoneal injection. Mice were sacrificed under anesthesia 24 h after triptolide treatment. Values are expressed as mean ± SD. n = 6.
P<0.05 compared to the control group.
P<0.01 compared to the control group.
P<0.01 compared to the triptolide-treated group.