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. 2014 Jun 26;9:3119–3130. doi: 10.2147/IJN.S61823

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© 2014 Baskaran et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Cumulative in vitro release profile of curcumin from LCN dispersions in phosphate-buffered saline (pH 7.4) at 37°C.

Notes: Inset: percentage of curcumin remaining within the LCN at the end of the release study. The in vitro release of the three curcumin-loaded LCN dispersions was carried out using a dialysis bag (molecular weight cut-off: 3,500 g/mole), and it revealed a sustained release pattern, especially for LCN-P. Each value represents the mean ± standard deviation (n=3).

Abbreviations: LCN, liquid crystalline nanoparticles; LCN-P, liquid crystalline nanoparticles prepared with polyethylene glycol 400 as a solubilizer; LCN-R, liquid crystalline nanoparticles prepared with Cremophor RH 40 as a solubilizer; LCN-PR, liquid crystalline nanoparticles prepared with polyethylene glycol 400 and Cremophor RH 40 as solubilizers; n, number.