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. 2014 Jul 2;9(7):e101444. doi: 10.1371/journal.pone.0101444

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© 2014 Sowa et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Classic serum parameters of liver damage, transient elastography, and sonographically diagnosed steatosis were assessed in NAFLD patients and ALD patients with (ALDC) or without (ALDNC) cirrhosis. While AST (B) and γGT (D) did not differ between the groups, ALT (A) and especially the ALT/AST ratio (C) were significantly higher in NAFLD patients than in both ALD groups. In contrast transient elastography (E), as measure for fibrotic/cirrhotic alterations, and incidence of steatosis (F) were similar in NAFLD and ALDNC patients. ALDC patients exhibited significantly higher transient elastography values and lower incidence of steatosis. *** = p<0.0001 vs. NAFLD. ## = p<0.01 vs. ALDC.