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. 2014 Jul 2;9(7):e101537. doi: 10.1371/journal.pone.0101537

Table 2. Lead Biomarkers, Serum Iron Indices and Genotypes by Exposure [Mean ± SD or N (%) or M (P25, P75)].

Grouping Exposed Unexposed
Males Females Males Females
BPb(µg/L) 384.54±151.98** 276.16±107.93** 144.72±60.22 139.91±56.84
UPb(µg/L) 39.00(18.00,80.00)** 28.50(12.00,51.50)** 3.00(1.00,7.00) 1.00(1.00,7.50)
ZPP(µg/gHb) 9.00±8.92** 9.03±8.24** 2.49±1.24 4.98±5.79
sFe (µmol/L) 20.97±7.90* 17.08±7.13 24.00±7.93 14.74±7.00
UIBC(µmol/L) 37.4±12.4 44.2±13.9* 35.4±12.7 51.1±14.8
TIBC(µmol/L) 56.90(51.79, 62.73) 61.3±10.8 57.83(52.65, 65.29) 65.9±12.1
Tf (g/L) 2.73±0.49 2.92±0.54 2.87±0.42 2.96±0.58
TfS (%) 34.80(26.10, 44.96)* 28.92±12.84 41.37(30.31, 49.68) 23.39±11.65
sFn (µg/L) 160.00(92.30, 230.00)** 38.90(20.95, 59.00) 238.00(148.00, 343.00) 42.20(20.70, 64.50)
sTfR (mg/L) 1.30(1.13, 1.55) 1.38(1.20, 1.56)* 1.36(1.12, 1.55) 1.26(0.99, 1.44)
BIC (mg/kg) 40.30±2.63** 35.22±3.28 41.74±2.67 35.46±2.69
Hb(g/L) 139.8±15.0 120.5±12.2 138.3±13.3 115.9±14.2
H63D
HH 546(94.8) 120(93.0) 39(90.7) 21(91.3)
HD 29(5.0) 9(7.0) 4(9.3) 2(8.7)
DD 1(0.2) 0 0 0
C282Y
CC 576(100) 129(100) 43(100) 23(100)
CY 0 0 0 0
YY 0 0 0 0

Abbreviations: BPb, blood lead; UPb, urine lead; ZPP, zinc protoporphyrin; sFe, serum iron; UIBC, unsaturated iron-binding capacity; TIBC, total iron binding capacity; Tf, transferrin; TfS, serum transferrin saturation; sFn, serum ferritin; sTfR, soluble transferrin receptor; BIC, body iron content; Hb, haemoglobin. For H63D genotype, HH, wild-type; HD, H63D heterozygous variant; DD, H63D homozygous variant. For C282Y genotype, CC, wild-type; CY, C282Y heterozygous variant; YY, C282Y homozygous variant.

*(**) p<0.05 (0.01) (Chi-square test, Student's t-test or nonparametric test) compared with the unexposed group of the same sex.

Results were expressed as the mean ± SD when continuous variables followed a normal distribution.

Results were expressed as M (P25, P75) when continuous variables did not follow a normal distribution.