Table 3. Results of gene expression analysis in the clinical setting of 267 patients with multivariate Cox and Kaplan-Meier method.
P-value from KM | P-value from Cox | Range risk ratio | Range risk ratio lower limit | Range risk ratio upper limit | |
ANO1 | 0.000455 | 0.001999 | 251.7049 | 7.554459 | 8386.487 |
MID1 | 0.022369 | 0.00219 | 0.061488 | 0.010323 | 0.366259 |
KANK4 | 0.00051 | 0.014574 | 29.03691 | 1.946079 | 433.2518 |
IGFBP3 | 0.000968 | 0.021595 | 14.17555 | 1.476178 | 136.1259 |
KLF6 | 0.239788 | 0.02687 | 0.130799 | 0.021595 | 0.792224 |
GLI3 | 0.114457 | 0.038389 | 0.115389 | 0.014944 | 0.890962 |
SMCR7L | 0.037868 | 0.04224 | 9.413194 | 1.081742 | 81.91252 |
NEK6 | 0.066407 | 0.050178 | 133.963 | 0.996207 | 18014.43 |
NAT2 | 0.356728 | 0.065965 | 7.387218 | 0.876405 | 62.26683 |
PBX3 | 0.140048 | 0.072855 | 0.076392 | 0.004598 | 1.26913 |
ANGPT2 | 0.000343 | 0.073683 | 21.83904 | 0.744166 | 640.9105 |
AIMP2 | 0.431665 | 0.07928 | 16.0743 | 0.722844 | 357.4535 |
OSBPL3 | 8.41E-05 | 0.08083 | 4.974909 | 0.821414 | 30.13061 |
ATXN1 | 0.020848 | 0.102364 | 8.834232 | 0.646996 | 120.6247 |
TUBB3 | 0.019182 | 0.106898 | 3.208144 | 0.777738 | 13.2335 |
TPBG | 0.009543 | 0.109652 | 3.902565 | 0.735954 | 20.69425 |
IGF1R | 0.134023 | 0.110324 | 9.739804 | 0.595836 | 159.2113 |
EZR | 0.016156 | 0.117108 | 17.77504 | 0.485969 | 650.1487 |
SAV1 | 0.011384 | 0.118547 | 14.03151 | 0.509015 | 386.7929 |
AR | 0.348534 | 0.121365 | 0.161848 | 0.01616 | 1.621013 |
RAI14 | 0.00433 | 0.131537 | 3.122865 | 0.710897 | 13.71828 |
CXCR4 | 0.05891 | 0.140109 | 0.269459 | 0.047199 | 1.53833 |
UST | 0.013135 | 0.140332 | 7.706586 | 0.510569 | 116.324 |
INHBA | 0.002297 | 0.145151 | 3.199909 | 0.669214 | 15.30066 |
CCL5 | 0.07661 | 0.146705 | 0.218204 | 0.027924 | 1.705063 |
STC1 | 0.047976 | 0.154726 | 11.71039 | 0.395198 | 346.9982 |
CALU | 0.540614 | 0.173061 | 0.215761 | 0.02376 | 1.959315 |
CD109 | 0.159253 | 0.178425 | 5.255192 | 0.46883 | 58.90633 |
DICER1 | 0.166057 | 0.19096 | 0.255369 | 0.033012 | 1.975454 |
HIF1A | 0.779411 | 0.208162 | 0.362001 | 0.074392 | 1.76154 |
MKI67 | 0.007381 | 0.224242 | 3.396451 | 0.472755 | 24.40137 |
VAV3 | 0.024025 | 0.224528 | 0.47273 | 0.141103 | 1.583763 |
TFAM | 0.482992 | 0.240308 | 10.34319 | 0.209424 | 510.8378 |
BGN | 0.013917 | 0.24456 | 2.629649 | 0.516015 | 13.40088 |
UGCG | 0.133881 | 0.245772 | 18.61169 | 0.133532 | 2594.106 |
PLK2 | 0.121792 | 0.271772 | 7.080799 | 0.215788 | 232.3469 |
CAV2 | 0.095172 | 0.276778 | 2.660236 | 0.456206 | 15.51242 |
BBX | 0.374652 | 0.279638 | 12.47811 | 0.128517 | 1211.536 |
SNAI1 | 0.183131 | 0.282896 | 0.363617 | 0.057377 | 2.304384 |
MCL1 | 0.231297 | 0.283847 | 0.295541 | 0.031804 | 2.746347 |
COX7A2L | 0.122784 | 0.285949 | 0.277405 | 0.026316 | 2.924187 |
CEP170 | 0.018982 | 0.299886 | 4.728032 | 0.250678 | 89.17529 |
CCND1 | 0.171718 | 0.300918 | 3.251198 | 0.348254 | 30.35228 |
COMMD2 | 0.077355 | 0.303629 | 5.395563 | 0.217408 | 133.9053 |
ADAMTS5 | 0.123317 | 0.305862 | 2.314392 | 0.464361 | 11.535 |
ESR2 | 0.153752 | 0.311968 | 2.66113 | 0.399116 | 17.74326 |
KLF12 | 0.465026 | 0.319069 | 2.64606 | 0.390215 | 17.943 |
CCL2 | 0.441674 | 0.319525 | 0.438755 | 0.086651 | 2.22162 |
EPAS1 | 0.490625 | 0.331663 | 0.418505 | 0.072098 | 2.429288 |
RTN2 | 0.249843 | 0.334748 | 2.735875 | 0.353963 | 21.14633 |
CHST13 | 0.039054 | 0.336699 | 2.876949 | 0.33316 | 24.84341 |
PIM1 | 0.105052 | 0.367117 | 3.552454 | 0.226011 | 55.83778 |
PPP2CA | 0.19979 | 0.373204 | 0.317213 | 0.025341 | 3.970806 |
CLOCK | 0.209762 | 0.374067 | 0.492709 | 0.103457 | 2.346506 |
FAM84A | 0.107645 | 0.37997 | 0.496851 | 0.104249 | 2.367992 |
TM4SF1 | 0.158023 | 0.392541 | 3.496384 | 0.198371 | 61.62552 |
CAMK2D | 0.703007 | 0.396634 | 1.968245 | 0.411242 | 9.420213 |
HIPK1 | 0.368779 | 0.397418 | 0.322743 | 0.023514 | 4.429794 |
KLF5 | 0.089271 | 0.408022 | 0.523601 | 0.113069 | 2.42469 |
PTEN | 0.554417 | 0.413923 | 0.412612 | 0.049346 | 3.450134 |
MYOF | 0.275264 | 0.417654 | 5.561907 | 0.087722 | 352.6461 |
PNRC1 | 0.318134 | 0.420618 | 3.398165 | 0.173127 | 66.69977 |
IGF2R | 0.096886 | 0.429115 | 2.60505 | 0.242724 | 27.95882 |
HGF | 0.003672 | 0.429973 | 2.099431 | 0.332818 | 13.24333 |
CDKN1A | 0.059386 | 0.430643 | 0.388964 | 0.037156 | 4.071878 |
TGFB1 | 0.006336 | 0.446801 | 2.421279 | 0.248095 | 23.63038 |
KDR | 0.18116 | 0.449974 | 1.72842 | 0.417918 | 7.14838 |
EPHA3 | 0.567195 | 0.472304 | 0.55043 | 0.108045 | 2.804128 |
CFTR | 0.384598 | 0.47535 | 2.360475 | 0.223261 | 24.95658 |
ARNT2 | 0.06533 | 0.481856 | 0.413958 | 0.035442 | 4.834986 |
MITF | 0.110527 | 0.487799 | 1.829958 | 0.331946 | 10.08821 |
AHNAK2 | 0.188641 | 0.495026 | 1.774388 | 0.341724 | 9.213451 |
KLF7 | 0.049811 | 0.506272 | 1.612536 | 0.39409 | 6.598172 |
JAK2 | 0.394445 | 0.516395 | 0.591344 | 0.120979 | 2.890488 |
SOX2 | 0.150192 | 0.541916 | 0.530877 | 0.069385 | 4.061828 |
MAPRE1 | 0.357987 | 0.543075 | 0.557944 | 0.085098 | 3.658149 |
CDH1 | 0.03582 | 0.552333 | 1.615003 | 0.332349 | 7.847868 |
IGSF5 | 0.019559 | 0.555833 | 1.679289 | 0.29926 | 9.423273 |
ANTXR2 | 0.546413 | 0.565429 | 3.671851 | 0.043523 | 309.7803 |
PLK1 | 0.416995 | 0.572943 | 0.671878 | 0.168582 | 2.677758 |
MECP2 | 0.462499 | 0.581138 | 0.626129 | 0.118665 | 3.303723 |
VAMP2 | 0.161211 | 0.58226 | 0.628316 | 0.119973 | 3.290569 |
COL1A1 | 0.02623 | 0.584364 | 0.529685 | 0.054348 | 5.162451 |
FES | 0.382467 | 0.593556 | 1.591399 | 0.288902 | 8.766134 |
PTK2 | 0.060876 | 0.601408 | 1.649351 | 0.25232 | 10.78138 |
BCL2 | 0.338186 | 0.610589 | 0.626785 | 0.103814 | 3.784251 |
HOXB5 | 0.27284 | 0.62191 | 1.486459 | 0.307571 | 7.183917 |
CYP39A1 | 0.486591 | 0.642143 | 1.671365 | 0.191529 | 14.58506 |
CDX2 | 0.002486 | 0.683233 | 0.651889 | 0.083486 | 5.090169 |
PDGFRB | 0.042645 | 0.69718 | 1.42049 | 0.242459 | 8.322194 |
CD59 | 0.005198 | 0.700335 | 1.635662 | 0.133489 | 20.04205 |
EPHB2 | 0.042245 | 0.744099 | 0.655446 | 0.051878 | 8.281188 |
FAM1738 | 0.112702 | 0.744395 | 1.849962 | 0.045828 | 74.67826 |
SHMT2 | 0.040828 | 0.745961 | 0.73874 | 0.118273 | 4.614223 |
SLC12A2 | 0.434188 | 0.771848 | 0.776719 | 0.140768 | 4.285722 |
HOXB7 | 0.195627 | 0.788445 | 0.798834 | 0.154871 | 4.120429 |
PBK | 0.445747 | 0.790426 | 0.821722 | 0.193118 | 3.496454 |
DUSP10 | 0.13842 | 0.794739 | 1.669082 | 0.03519 | 79.16626 |
CISH | 0.090655 | 0.810002 | 0.754679 | 0.076079 | 7.486208 |
FAP | 0.030751 | 0.811833 | 1.191001 | 0.282441 | 5.022236 |
MAFF | 0.255153 | 0.814144 | 0.748927 | 0.067236 | 8.342135 |
MET | 0.13437 | 0.823224 | 1.374103 | 0.084554 | 22.33087 |
CHEK1 | 0.163926 | 0.825053 | 0.822722 | 0.145827 | 4.641614 |
ESR1 | 0.056936 | 0.846116 | 1.3123 | 0.084339 | 20.41915 |
CDX1 | 0.010579 | 0.848595 | 1.30181 | 0.086808 | 19.52242 |
ADM | 0.262582 | 0.853341 | 1.156516 | 0.247503 | 5.40409 |
HECTD2 | 0.353439 | 0.855316 | 0.860183 | 0.170415 | 4.341829 |
PPARGC1B | 0.37968 | 0.855611 | 1.222648 | 0.14027 | 10.65707 |
LDLR | 0.355447 | 0.858784 | 1.222084 | 0.134155 | 11.13256 |
HIC2 | 0.176202 | 0.862587 | 0.815525 | 0.081015 | 8.209401 |
CHEK2 | 0.155676 | 0.866904 | 1.172525 | 0.182286 | 7.542064 |
AXL | 0.039057 | 0.882521 | 1.167514 | 0.149675 | 9.107027 |
SRC | 0.503974 | 0.883268 | 0.895666 | 0.205758 | 3.898842 |
FGFR1 | 0.416422 | 0.892855 | 0.896111 | 0.181618 | 4.421444 |
CXCL10 | 0.090745 | 0.898925 | 0.868597 | 0.098801 | 7.636207 |
ETS2 | 0.135175 | 0.904279 | 0.80061 | 0.021349 | 30.02398 |
KIF11 | 0.243986 | 0.91388 | 0.918496 | 0.196749 | 4.287873 |
ROCK1 | 0.302625 | 0.915522 | 1.123317 | 0.131032 | 9.630014 |
DROSHA | 0.25995 | 0.924716 | 1.086434 | 0.194645 | 6.064063 |
JAK1 | 0.113129 | 0.930365 | 0.905077 | 0.096647 | 8.47581 |
ERBB2 | 0.302875 | 0.962123 | 1.048409 | 0.14901 | 7.376446 |
CTNNB1 | 0.099735 | 0.963275 | 1.03343 | 0.254908 | 4.18966 |
GBP1 | 0.040014 | 0.969138 | 1.043144 | 0.122758 | 8.864152 |
SLITRK4 | 0.238082 | 0.973046 | 0.978316 | 0.274291 | 3.489367 |