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. 2014 Jul 2;9(7):e101065. doi: 10.1371/journal.pone.0101065

Table 6. AUC analysis for the top 15 multidimensional biomarkers in the training and testing set.

AUC Combinations MB Training Test
DICER1+IGFBP3+Mir−29a+HGF_Index +ADAMTS5+OSBPL3_Cyto_AQUA+ETS2+EPHA3+SHMT2+ESR1 1 0.91059 0.89881
ADAMTS5+OSBPL3_Cyto_AQUA+HGF_Index+ESR2+ANGPT2+HGF_Nuclear_AQUA+ARNT2+IGFBP3+Mir−29a+HGF_Cyto_AQUA 2 0.921007 0.871599
CD109+IGFBP3+Let−7c+CISH+KLF7+CDX1+MITF+ADAMTS5+ANO1+ANTXR2 3 0.914251 0.861305
HOXB7+IGFBP3+Mir−141+HGF_Index+ESR1+ANO1+PLK2+OSBPL3_AQUA+COX7A2L+IGFBP3_Stroma_AQUA 4 0.865103 0.899916
HOXB7+IGFBP3+MiR−320+HGF_Index+DROSHA+KLF6+Mir−200a+FGFR1+TM4SF1+Mir−200b 5 0.916084 0.847826
IGFBP3+Mir−29a+PNRC1+HGF_Index+CFTR+SRC+KLF5+KIF11+ANO1+CAV2 6 0.903652 0.855797
EZR+Mir−17+HGF_Index+ANO1+IGFBP3_AQUA+OSBPL3_AQUA+Mir−200b+PIM1+ANO1_AQUA+PPP2CA 7 0.827957 0.930193
EZR+Mir−200a+HGF_Index+IGFBP3+Mir−17+ESR1+Mir−92a+ERBB2+DUSP10+PLK2 8 0.868687 0.881884
DICER1+IGFBP3+MiR−193a−5p+CDX1+DROSHA+ANTXR2+HGF_Index+KIF11+OSBPL3_Cyto_AQUA+PLK2 9 0.875868 0.872449
RAI14+HGF_Index+STC1+MiR−18a+COX7A2L+SOX2+SMCR7L+NAT2+MCL1+ANTXR2 10 0.845377 0.88913
HOXB7+IGFBP3+Mir−141+HGF_Index+ESR1+ANO1+PLK2+OSBPL3_AQUA+COX7A2L 11 0.844618 0.885606
IGFBP3+Mir−29a+PNRC1+HGF_Index+CFTR+SRC+KLF5+KIF11+ANO1 12 0.885781 0.843478
HOXB7+IGFBP3+MiR−320+HGF_Index+DROSHA+KLF6+Mir−200a+FGFR1 13 0.862471 0.845652
DICER1+IGFBP3+Let−7g+CDX1+ANTXR2+ADM+DROSHA+KLF6+TUBB3_Cyto_AQUA+HGF_Cyto_AQUA 14 0.86748 0.837662
EZR+Mir17+HGF_Index+ANO1+IGFBP3_AQUA+OSBPL3_AQUA+Mir−200b+PIM1+ANO1_AQUA 15 0.839687 0.849453