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. 2014 Jun 18;45(1):66. doi: 10.1186/1297-9716-45-66

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Copyright © 2014 Wei et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Amino acid sequence alignment of Muscovy duck MDA5 protein with other MDA5 proteins. Accession numbers: human (accession numbers; NP_071451), mouse (NP_082111) and chicken (NP_001180567). The predicted motifs for CARD are indicated with gray bars on the alignment. The predicted motifs for DExD/H box RNA helicase domains are indicated by numbers (I-VI) and lines. Two predicted Zn²⁺-binding motifs and an RNA binding loop are indicated with black lines and a box. MDA5 sequences are shown for Muscovy duck (Md), human (Hu), mouse (Mo) and chicken (Ch).