Table 1.
Demographic and clinical characteristics by ANKK1 and DRD2 genotype
| Gene |
ANKK1
|
DRD2
|
||
|---|---|---|---|---|
| TT/TC | CC | TT/TG | GG | |
| Characteristic | ||||
| N | 21 | 26 | 10 | 37 |
| Male (%) | 81 | 92.3 | 70 | 91.9 |
| African American (%) | 76.2 | 61.5 | 50 | 73 |
| Caucasian (%) | 9.5 | 11.5 | 20 | 8.1 |
| Hispanic (%) | 4.8 | 11.5 | 10 | 8.1 |
| Other (%) | 9.5 | 15.5 | 20 | 10.8 |
| Education, years (SD) | 12.5 (2) | 13 (1.6) | 13.2 (2.4) | 12.7 (1.6) |
| Age (SD) | 42.3 (6.1) | 44.5 (7) | 40.4 (7) | 44.4 (6.3) |
| Weight (SD) | 183.4 (38) | 190.9 (30) | 181.3 (41) 189.2 (32) | |
| Cocaine use, years (SD) | 16.3 (6.7) | 16.2 (8) | 17.5 (7.3) | 15.9 (7.4) |
| Cocaine use, daily (SD) | 4.9 (6.4) | 4.1 (4) | 6.5 (8.7) | 3.9 (3.7) |
| Cocaine use, past 30 days (SD) | 17.7 (7.4) | 16.1 (7.9) | 17.3 (7.3) | 16.7 (7.8) |
| Grams used per day (SD) | 2.7 (3.1) | 1.6 (1.2) | 3.5 (3.8) | 1.6 (1.3) |
| Nicotine use, years (SD)* | 17.4 (8.5) | 22.7 (7.7) | 14.9 (5.4) | 21.5 (8.6) |
*
The only significant difference among the demographic variables is for years of nicotine use for ANKK1 p = 0.0432 and DRD2 p = 0.0133. No significant baseline differences in any clinical characteristics were observed after adjusting for multiple testing (p > 0.05).