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. 2012 Jun 13;6(4):367–375. doi: 10.1007/s11571-012-9207-z

Table 1.

Regular-spiking pyramidal neurons

Description Equations Parameters
Somatic voltage Inline graphic C m = 1 μF/cm2
I syn,s − g sd(V s − V d) + I ext A s = 0.015 mm2
g sd = (1.75 ± 0.1) μS
Dendritic voltage Inline graphic A d = 0.035 mm2
I syn,d − g sd(V d − V s) + I ext
Inline graphic
Inline graphic
Leakage current I L = g L (V − V L) V L = (−60.95 ± 0.3) mV
g L = (0.067 ± 0.0067) mS/cm2
Spiking sodium current Inline graphic g Na = 50 mS/cm2
Inline graphic V Na = 55 mV
Inline graphic ϕ = 4
Inline graphic
Inline graphic
Inline graphic
Inline graphic
Spiking potassium current I K = g K h 4K(V − V K) ϕ = 4
Inline graphic g K = 10.5 mS/cm2
Inline graphic V K =  −100 mV
Inline graphic
Fast inactivating current Inline graphic g A = 1 mS/cm2
Inline graphic Inline graphic
Inline graphic
Inline graphic
Non-inactivating K+-channel I KS = g KS m KS(V − V K) g KS = 0.576 mS/cm2
Inline graphic
Inline graphic
Inline graphic
Non-inactivating sodium channel Inline graphic g NaP = 0.0686 mS/cm2
Inline graphic
Hyperpolarization de-inactivated channel Inline graphic g AR = 0.0257 mS/cm2
Inline graphic
High-threshold Ca2+-channel Inline graphic g Ca = 0.43 mS/cm2
Inline graphic V Ca = 120 mV
Calcium dependent potassium channel I KCa = g KCa[Ca2+]/([Ca2+] + K D)(V − V K) g KCa = 0.57 mS/cm2
d [Ca2+]/dt =  −αCa A d I Ca − [Ca2+]/τCa Inline graphic
τCa = 150 ms
Sodium dependent potassium channel Inline graphic g KNa = 1.33 mS/cm2
Inline graphic
Sodium dynamics d [Na+]/dt =  − αNa(A s I Na + A d I NaP) Inline graphic
R pump{[Na+]3/([Na+]3 + 153) − [Na+]3eq/([Na+]3eq + 153)} R pump = 0.018 mM/ms
[Na+]eq = 9.5 mM