Somatic voltage |
|
C
m = 1 μF/cm2
|
− I
syn,s − g
sd(V
s − V
d) + I
ext
|
A
s = 0.015 mm2
|
g
sd = (1.75 ± 0.1) μS |
Dendritic voltage |
|
A
d = 0.035 mm2
|
− I
syn,d − g
sd(V
d − V
s) + I
ext
|
|
|
|
|
|
Leakage current |
I
L = g
L (V − V
L) |
V
L = (−60.95 ± 0.3) mV |
g
L = (0.067 ± 0.0067) mS/cm2
|
Spiking sodium current |
|
g
Na = 50 mS/cm2
|
|
V
Na = 55 mV |
|
ϕ = 4 |
|
|
|
|
|
|
|
|
Spiking potassium current |
I
K = g
K
h
4K(V − V
K) |
ϕ = 4 |
|
g
K = 10.5 mS/cm2
|
|
V
K = −100 mV |
|
|
Fast inactivating current |
|
g
A = 1 mS/cm2
|
|
|
|
|
|
|
Non-inactivating K+-channel |
I
KS = g
KS
m
KS(V − V
K) |
g
KS = 0.576 mS/cm2
|
|
|
|
|
|
|
Non-inactivating sodium channel |
|
g
NaP = 0.0686 mS/cm2
|
|
|
Hyperpolarization de-inactivated channel |
|
g
AR = 0.0257 mS/cm2
|
|
|
High-threshold Ca2+-channel |
|
g
Ca = 0.43 mS/cm2
|
|
V
Ca = 120 mV |
Calcium dependent potassium channel |
I
KCa = g
KCa[Ca2+]/([Ca2+] + K
D)(V − V
K) |
g
KCa = 0.57 mS/cm2
|
d [Ca2+]/dt = −αCa
A
d
I
Ca − [Ca2+]/τCa
|
|
τCa = 150 ms |
Sodium dependent potassium channel |
|
g
KNa = 1.33 mS/cm2
|
|
|
Sodium dynamics |
d [Na+]/dt = − αNa(A
s
I
Na + A
d
I
NaP) |
|
−R
pump{[Na+]3/([Na+]3 + 153) − [Na+]3eq/([Na+]3eq + 153)} |
R
pump = 0.018 mM/ms |
[Na+]eq = 9.5 mM |