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. 2014 Jun 28;14:472. doi: 10.1186/1471-2407-14-472

Table 2.

MMP1 expression in tumor cells and tumor stroma

Variable  
 MMP1 expression histoscore in tumor cells
 MMP1 expression histoscore in tumor associated stroma
N Mean SEM Median P-value Mean SEM Median P-value
All
 149
 32.8
 3.4
 15
 NA
 49.1
 5.1
 20
 NA
T-stage
  
  
  
  
  
  
  
  
  
1
 105
 30.6
 4.0
 14
 0.28
 49.7
 6.1
 20
 0.76
> 1
 44
 44.0
 38.2
 17
  
 43.0
 47.6
 20
  
N-stage
  
  
  
  
  
  
  
  
  
0
 91
 32.1
 4.4
 14
 1.00
 44.7
 6.5
 20
 0.29
> 1
 58
 34.0
 5.5
 18
  
 55.9
 8.1
 20
  
Grade
  
  
  
  
  
  
  
  
  
1 and 2
 95
 27.0
 4.2
 10
 0.007
 37.9
 6.2
 6
 0.0006
3
 54
 43.2
 5.6
 30
  
 69.2
 8.3
 50
  
Histology
  
  
  
  
  
  
  
  
  
IDC
 128
 34.3
 3.7
 20
 0.15
 53.8
 5.4
 20
 0.0022
Other
 21
 23.6
 9.0
 4
  
 20.8
 13.3
 1
  
Hormone receptor status
  
  
  
  
  
  
  
  
  
Negative
 19
 42.0
 9.5
 20
 0.26
 70.7
 14.5
 50
 0.18
Positive
 130
 31.5
 3.6
 13
  
 46.1
 5.4
 20
  
HER2 status
  
  
  
  
  
  
  
  
  
Negative
 127
 30.4
 3.7
 10
 0.18
 45.0
 5.5
 20
 0.29
Amplified
 22
 47.1
 8.8
 25
  
 72.5
 13.1
 40
  
Ki 67 (cut-off 20%)
  
  
  
  
  
  
  
  
  
Low
 92
 28.6
 4.3
 10
 0.04
 34.7
 6.2
 10
 0.0006
High
 56
 39.7
 5.5
 25
  
 72.8
 7.9
 50
  
Lymphovascular invasion
  
  
  
  
  
  
  
  
  
Present
 35
 41.0
 7.0
 20
 0.10
 48.2
 10.5
 20
 0.83
Absent
 114
 30.3
 3.9
 11
  
 49.4
 5.8
 20
  
Baseline CTC
  
  
  
  
  
  
  
  
  
CTC Epithelial
  
  
  
  
  
  
  
  
  
Negative
 133
 32.9
 3.6
 16
 0.35
 48.6
 5.4
 20
 0.50
Positive
 16
 32.1
 10.4
 3
  
 53.0
 15.5
 11
  
CTC EMT
  
  
  
  
  
  
  
  
  
Negative
 126
 30.2
 3.7
 10
 0.02
 45.7
 5.5
 20
 0.05
Positive
 23
 47.0
 8.6
 40
  
 68.5
 13.1
 50
  
CTC Any
  
  
  
  
  
  
  
  
  
Negative
 113
 31.3
 3.9
 10
 0.47
 47.9
 5.8
 20
 0.75
Positive 36 37.5 6.9 20   53.0 10.5 20