Table 5.
SNVs of multidrug resistant efflux pump genes and MICs of CLR
|
Strain |
MICs of CLR (μg/ml) |
hp0605 (hefA )
|
hp0606 (hefB )
|
hp0607 (hefC )
|
hp0969 (hefF )
|
hp0970 (hefE )
|
hp097
1
(hefD )
|
hp1327 (hefG )
|
hp1328 (hefH )
|
hp1329 (hefI )
|
hp1487
|
hp1488
|
hp1489
|
Total |
|
CLR-susceptible | ||||||||||||||
| 177 |
- |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| 179 |
- |
29 |
12 |
70 |
51 |
13 |
3 |
22 |
16 |
47 |
30 |
26 |
31 |
350 |
| 189 |
- |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| F32 |
- |
48 |
20 |
76 |
83 |
24 |
27 |
0 |
0 |
0 |
0 |
0 |
0 |
278 |
| F44 |
- |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| F65 |
- |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| F79 |
- |
39 |
15 |
49 |
55 |
16 |
30 |
0 |
0 |
0 |
0 |
0 |
0 |
204 |
|
CLR-resistant | ||||||||||||||
| S1 |
32 |
32 |
17 |
51 |
55 |
9 |
25 |
23 |
18 |
61 |
23 |
13 |
27 |
354 |
| S2 |
32 |
50 |
18 |
74 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
142 |
| S4 |
32 |
39 |
18 |
67 |
55 |
16 |
26 |
0 |
0 |
0 |
0 |
0 |
0 |
221 |
| S8 |
4 |
44 |
19 |
67 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
130 |
| S13 |
16 |
52 |
21 |
80 |
76 |
22 |
31 |
0 |
0 |
0 |
0 |
0 |
0 |
282 |
| S16 |
16 |
54 |
23 |
81 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
158 |
| S17 |
32 |
48 |
19 |
87 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
154 |
| S22 |
64 |
46 |
16 |
69 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
131 |
| S23 |
16 |
1 |
16 |
21 |
14 |
2 |
8 |
38 |
10 |
71 |
23 |
19 |
42 |
265 |
| S26 |
32 |
55 |
24 |
83 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
162 |
| 174 |
- |
40 |
11 |
55 |
58 |
19 |
34 |
26 |
10 |
52 |
27 |
19 |
47 |
398 |
| 194 |
- |
25 |
7 |
34 |
48 |
15 |
18 |
0 |
0 |
0 |
0 |
0 |
0 |
147 |
| Statistics | ||||||||||||||
| P value |
|
0.011 |
0.017 |
0.038 |
NS |
NS |
NS |
NS |
NS |
NS |
NS |
NS |
NS |
NS |
| 95% CI | 6.1-41.7 | 2.5-18.8 | 2.5-69.9 | |||||||||||
NS; not significant.