Table 3.
Examples of immune genes that responded to the functional feeds
| Genbank Or Probename | Gene, Symbol | 0 wpc | 6 wpc | 8 wpc | 14 wpc | ||||
|---|---|---|---|---|---|---|---|---|---|
| CMS1 | CMS2 | CMS1 | CMS2 | CMS1 | CMS2 | CMS1 | CMS2 | ||
| Antiviral responses | |||||||||
| BQ035726 | Very large inducible GTPase 1-3, vlig | −3.71 | −1.87 | −1.30 | −2.75 | −3.53 | −4.80 | −1.51 | −3.71 |
| ? | IFN inducible mx protein | −5.37 | −2.61 | 1.23 | 0.78 | −1.77 | −4.04 | −1.09 | −1.08 |
| DY741158 | STAT2 | −2.70 | −4.19 | 1.26 | 1.03 | 1.06 | −1.67 | 1.20 | 1.08 |
| CB500614 | Pyrin, bty | −1.38 | −2.76 | 1.12 | −1.03 | −2.39 | −3.50 | −1.79 | −1.14 |
| BX909789 | IRF4 | 2.82 | 2.64 | 3.28 | 1.46 | −1.73 | −2.14 | 1.31 | −1.06 |
| 213061919 | IRF7 | 3.33 | 4.43 | −1.01 | −1.19 | 1.54 | −1.18 | 1.27 | 1.45 |
| DW538275 | Receptor-transporting protein 3 | −1.90 | −2.31 | −0.09 | −0.43 | −0.85 | −1.17 | 0.45 | −0.13 |
| T cells | |||||||||
| Ssa#TC108524 | MHC class I antigen | −2.33 | −1.57 | −0.36 | −1.02 | −0.05 | −0.34 | −0.33 | −0.52 |
| ? | IFNg | −1.66 | −1.09 | −2.18 | −1.98 | −2.44 | −1.99 | −1.32 | −1.91 |
| AY693394 | CD8 beta | 1.19 | −1.35 | −2.07 | −1.76 | −2.02 | −1.43 | −1.60 | −1.74 |
| CA368982 | Kidney injury molecule 1, havcr1 | 1.36 | −1.31 | −1.46 | −1.64 | −4.27 | −2.62 | −1.36 | 1.19 |
| DY710412 | Granzyme A-1, graa | −2.24 | 1.30 | −2.65 | −2.18 | −3.04 | −2.94 | −1.04 | −2.07 |
| ? | Granzyme A-2, graa | −1.48 | −1.11 | −2.76 | −3.27 | −3.56 | −2.50 | −1.19 | −2.61 |
| CR369847 | NF activated T-cells calcineurin-dependent 1, nfatc1 | −1.10 | 2.27 | −1.63 | −1.03 | 4.62 | 3.09 | −1.88 | −1.35 |
| Inflammatory markers, regulators | |||||||||
| 213077403 | TNF alpha-induced protein 2, tnfaip2 | 2.53 | 2.48 | −3.51 | −1.35 | −2.53 | −2.29 | 2.03 | 1.11 |
| EG871595 | c3a anaphylatoxin chemotactic receptor, c3ar1 | −1.02 | 1.53 | 1.12 | 1.13 | −2.53 | −1.84 | −1.17 | −1.77 |
| DW576911 | Cytochrome P450 family 2 subfamily V, cyp2u1 | −1.90 | 1.13 | −5.38 | −2.73 | −1.74 | −2.67 | −2.35 | −1.54 |
| 213081824 | FcRgamma-like protein, fcer1g | −6.40 | −3.06 | −2.44 | 1.16 | −3.18 | −2.05 | 1.20 | −2.59 |
| EG881931 | TNF decoy receptor, tnfrsf6b | 1.36 | 1.13 | −1.73 | −1.69 | −2.96 | −3.18 | 1.21 | −1.10 |
| 213081931 | Helicase lymphoid-specific, hells | 2.24 | 4.47 | 1.34 | 2.20 | −2.25 | −1.98 | −1.06 | 1.41 |
| CK888744 | fetuin B | 1.16 | 1.39 | 0.87 | 1.19 | 1.42 | 0.58 | 1.51 | −0.56 |
| S48406409 | Ly75/CD205 | 2.79 | 2.75 | −1.13 | −1.31 | 2.06 | 1.55 | −1.27 | −1.34 |
Data are expression ratios (fold changes) of fish fed the functional feeds (CMS1 and CMS2) relative to the REF diet during the course of the infection.