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Induction of Hh target genes during ischemia-reperfusion (I/R) is dependent on Gi proteins. Expression of Gli1 was normalized to S15 in the left ventricle of TTA and GiCT/TTA mice without Doxy supplementation that were subjected to sham surgery or to 30-min ischemia by ligation of the left anterior descending coronary artery followed by 72 h of reperfusion (I/R). n = 6. *P < 0.01; **P < 0.001.
