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Simulation of individual aspects of ischemia. A: reduction of action potential amplitude. B: shortening of action potential duration. Each panel shows, on the top, the action potential at baseline (black) and after the changes are applied. The part on bottom depicts the extent of the changes on the heart model on the left and the resulting electrocardiogram (ECG) on the right, both at baseline condition (black) then after changes (red). ECG, electrocardiogram; AP, action potential.
