Table 3.
Selected studies evaluating radiolabeled somatostatin analogs for treatment of NETs
| Study | N | Radiolabeled somatostatin analog | Response rates (PR+CR) | Symptom relief or reduction | Median overall survival |
|---|---|---|---|---|---|
| Bushnell, 2010 USA | 90 | 90-Y-edotreotide | 4% | >50% | 26.9 months |
| Delpassand, 2008 USA | 18 | In-111 pentetreotide | 11% | NA | 13.3 months |
| Kwekkeboom 2008 Netherlands | 310 | Lu-177-octreotate | 30% | NA | 46 months |
| Forrer 2006 Switzerland | 116 | 90-Y-DOTATOC | 27% | 83% | NA |
| Anthony 2002 USA | 26 | In-111 pentetreotide | 8% | 62% | 18 months |
Abbreviations: CR, complete remission; In-111, indium 111; Lu-177, leutium-177; NA, not available; PR, partial remission; 90-Y, 90-yttrium.