Table 5.
t-tests of microarray measurements between genotype and DNA methylation for blood, normal and tumor tissues.
| Nsp | |||
|---|---|---|---|
| Genotype | DNA methylation | P-value | |
| blood | 1.32 | 1.19 | 3.1 × 10−12 |
| normal tissue | 2.45 | 1.75 | ∗ |
| tumor | 2.84 | 2.23 | ∗ |
| Sty1 | |||
| Genotype | DNA methylation | P-value | |
| blood | 2.21 | 1.77 | ∗ |
| normal tissue | 2.58 | 2.14 | ∗ |
| tumor | 2.87 | 2.48 | ∗ |
| Sty2 | |||
| Genotype | DNA methylation | P-value | |
| blood | 1.69 | 1.29 | ∗ |
| normal tissue | 2.42 | 2.02 | ∗ |
| tumor | 2.51 | 2.04 | ∗ |
Nsp and Sty are the microarray data sets used in the study. Sty1 and Sty2 correspond to the PC4 for genotype (Figures 4d and 6b)/PC3 for DNA methylation (Figures 5c and 6c) and PC3 for genotype (Figures 4c and 6a)/PC4 for DNA methylation (Figures 5d and 6d) combinations of PCs. ∗ indicates P-values <2.2 x 10−16.