Fig. 5.

FasL⁺ T lymphocytes enhance alveolar macrophage (AMΦ) apoptosis during the resolution of LPS-induced inflammation. A: Rag-1^−/− lymphocyte-deficient-recipient mice were treated with intratracheal LPS immediately followed by adoptive transfer of FasL-sufficient (WT) or FasL mutant (gld) lymphocytes by tail vein injection. B: total AMΦ counts in BAL fluid on day 9 following intratracheal LPS treatment and concurrent intravenous adoptive transfer of lymphocytes; n = 22 mice per group; 5 replicates. C: apoptosis of AMΦs measured by activated caspase-3 expression on day 9 following treatment; n = 9 mice per group; 2 replicates. *P < 0.05.