Table 2. Pain-related brain areas activated in response to painful video stimuli.
| Pain>no-pain area | Talairach atlas x-y-z (mm) | T | Z | P (FWE) | Cluster k |
|---|---|---|---|---|---|
| Lt AI/IFG | −42, 16, 0 | 7.80 | 6.24** | 0.000 | 237 |
| Lt AI/IFG | −42, 30, 16 | 6.67 | 5.58** | 0.000 | 78 |
| Lt AI/IFG | −48, 6, 32 | 6.33 | 5.37** | 0.000 | 293 |
| Rt AI/IFG | 42, 28, 16 | 5.72 | 4.97** | 0.001 | 417 |
| Rt AI/IFG | 34, 26, −4 | 5.39 | 4.74** | 0.003 | 58 |
| Lt TPJ | −56, −32, 32 | 8.54 | 6.63** | 0.000 | 763 |
| Rt TPJ | 56, −34, 24 | 8.79 | 6.75** | 0.000 | 762 |
Abbreviations: AI, anterior insula; FWE, family-wise error corrected; IFG, inferior frontal gyrus; Lt, left; Rt, right; TPJ, temporoparietal junction.
*P<0.05, **P<0.01.
The pain effect contrast was created by comparing the signal intensity during pain, compared with no-pain conditions.